Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9681
Gene Symbol: DEPDC5
DEPDC5
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.500 GeneticVariation GWASDB Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. 23242368

2013
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.500 GeneticVariation GWASDB We also found significantly lower mRNA expression of STAT4 in HCC tumor tissues compared with paired adjacent nontumor tissues (P = 2.33 × 10(-14)). 23242368

2013
Entrez Id: 23095
Gene Symbol: KIF1B
KIF1B
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.200 GeneticVariation GWASDB Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. 23242368

2013
Entrez Id: 23095
Gene Symbol: KIF1B
KIF1B
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.200 GeneticVariation GWASDB Genome-wide association study identifies 1p36.22 as a new susceptibility locus for hepatocellular carcinoma in chronic hepatitis B virus carriers. 20676096

2010
Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.180 GeneticVariation GWASDB Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. 23242368

2013
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.180 GeneticVariation GWASDB Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. 23242368

2013
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.150 GeneticVariation GWASDB Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. 23242368

2013
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.150 GeneticVariation GWASDB GWAS identifies novel susceptibility loci on 6p21.32 and 21q21.3 for hepatocellular carcinoma in chronic hepatitis B virus carriers. 22807686

2012
Entrez Id: 2897
Gene Symbol: GRIK1
GRIK1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.110 GeneticVariation GWASDB GWAS identifies novel susceptibility loci on 6p21.32 and 21q21.3 for hepatocellular carcinoma in chronic hepatitis B virus carriers. 22807686

2012
Entrez Id: 717
Gene Symbol: C2
C2
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.110 GeneticVariation GWASDB Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. 23242368

2013
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.110 GeneticVariation GWASDB Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. 23242368

2013
Entrez Id: 1589
Gene Symbol: CYP21A2
CYP21A2
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.100 GeneticVariation GWASDB Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. 23242368

2013
Entrez Id: 3118
Gene Symbol: HLA-DQA2
HLA-DQA2
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.100 GeneticVariation GWASDB Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. 23242368

2013
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.100 GeneticVariation GWASDB Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. 23242368

2013
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		1.000 Biomarker GENOMICS_ENGLAND

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		1.000 Biomarker GENOMICS_ENGLAND

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.800 Biomarker GENOMICS_ENGLAND

Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		1.000 GeneticVariation UNIPROT Our results indicate that mutations of the tyrosine kinase domain of the MET gene may be involved in the acceleration of the carcinogenesis in childhood HCC. 9927037

1999
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.800 GeneticVariation UNIPROT

Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.800 GeneticVariation UNIPROT Some of the PIK3CA mutations were detected in the early lesions of breast cancer carcinoma, hepatocellular carcinoma, and gastric carcinomas, suggesting that PIK3CA mutation may occur independent of stage of the tumors. 15608678

2005
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.800 GeneticVariation UNIPROT

Entrez Id: 8312
Gene Symbol: AXIN1
AXIN1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.800 GeneticVariation UNIPROT About half the HCCs with AXIN1 or AXIN2 mutations showed beta-catenin accumulation in the nucleus, cytoplasm or membrane. 12101426

2002
Entrez Id: 10553
Gene Symbol: HTATIP2
HTATIP2
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.600 GeneticVariation UNIPROT

Entrez Id: 1033
Gene Symbol: CDKN3
CDKN3
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.590 GeneticVariation UNIPROT Eight of 14 biopsy tissues obtained from advanced HCC, 6 of 13 surgically removed HCC tissues, and 2 of the adjacent noncancerous tissues contained aberrant KAP transcripts. 10987270

2000
Entrez Id: 10855
Gene Symbol: HPSE
HPSE
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.400 GeneticVariation UNIPROT